Radiocontrast Agents and Breastfeeding

From Issue: Volume 2, Issue 2

Radiocontrast Agents and Breastfeeding


Safe Radiocontrast Agents

Barium Sulfate

            Not absorbed orally, none will enter the milk

            No interruption in breastfeeding is necessary2

Bilopaque (Tyropanoate)

            Oral contrast agent for examining the gallbladder

            Levels in milk are unknown2

Gadolinium-Containing Radiocontrast Agents

“Review of the literature shows no evidence to suggest that oral ingestion by an infant of the tiny amount of gadolinium contrast agent excreted into breast milk would cause toxic effects. We believe, therefore, that the available data suggest that it is safe for the mother and infant to continue breastfeeding after receiving such an agent.”1


            Magnevist (Gadopentetate)

            Magnevistan (Gadopentetate)

            Magnograf (Gadopentetate)

            MultiHance (Gadobenate)


            Omniscan (Gadodiamide)

            Optimark (Gadoversetamide)

            Prohance (Gadoteridol)

            Viewgam (Gadopentetate)


Iodinated containing radiopaque medium (Ionic and Nonionic)

“Because of the very small percentage of iodinated contrast medium that is excreted into the breast milk and absorbed by the infant's gut, we believe that the available data suggest that it is safe for the mother and infant to continue breastfeeding after receiving such an agent.”1


Accupaque (Iohexol)

Amipaque (Metrizamide)

Angio-Conray (Iothalamate)

Angiocontrast (Metrizoate)

Angiovist (Diatrizoate)

Biliopaco (Iopromide)

Cardiografin (Diatrizoate)

Cholografin (Iodipamide)

Cistobil (Iopromide)

Clarograf (Iopromide)

Colegraf (Iopromide)

Colepak (Iopromide)

Conray-30 (Iothalamate)

Conray-43 (Iothalamate)

Conray-60 (Iothalamate)

Conray 325 (Iothalamate)

Conray-400, (Iothalamate)

Cyso-Conray (Iothalamate)

Cysto-Conray II (Iothalamate)

Cystografin (Diatrizoate)

Ethibloc (Diatrizoate)

Gastromiro (Iopamidol)

Gastrovist (Diatrizoate)

Hexabrix 160 (Ioxaglate)

Hexabrix 200 (Ioxaglate)

Hexabrix 320 (Ioxaglate)

Hexabrix (Ioxaglate)

Hypaque (Diatrizoate)

Isopaque (Metrizoate)

Iopamiro (Iopamidol)

Iopamiron (Iopamidol)

Iopasen (Iopamidol)

Isovue (Iopamidol)

Isovue-M (Iopamidol)

Jopamiro (Iopamidol)

Myelo-Kit (Iohexol)

Neocontrast (Iopromide)

Niopam (Iopamidol)

Omnigraf (Iohexol)

Omnipaque (Iohexol)

Omnitrast (Iohexol)

Optiject (Ioversol)

Optiray (Ioversol)

Pamiray (Iopamidol)

Proscope (Iopromide)

Radiomiron (Iopamidol)

Reno-30 (Diatrizoate)

Reno-60 (Diatrizoate)

Reno-Dip (Diatrizoate)

Renografin (Diatrizoate)

Reno-M (Diatrizoate)

Retrografin (Diatrizoate)

Scanlux (Iopamidol)

Sinografin (Diatrizoate)

Sinografin (Iodipamide)

Solutrast (Iopamidol)

Telebrix (Ioxitalamic Acid)

Telepaque (Iopanoic Acid)

Ultravist (Iopromide)

Urovist (Diatrizoate)

Vascoray (Iothalamate)

Visipaque (Iodixanol)



Radiocontrast Agent of Concern


Teslascan (Mangafodipir Trisodium)

            Manganese-containing radiocontrast agent                   A brief interruption of breastfeeding for 4 hours

            Rapidly redistributed to liver                                       followed by pumping and dumping her milk once

Save milk ahead of the test for one or two feedings    This would reduce any risk to the infant2




1American College of Radiology, Committee on Drugs and Contrast Media (2010). Administration of contrast media

            to breastfeeding mothers, ACR Manual on Contrast Media, Version 7.

2Hale T. (2010). Medications and mothers’ milk (14th Ed). Amarillo, TX: Hale Publishing. pp. 1150-1151, 1153

Infant-Risk Center—Call to check if medications compatible with breastfeeding (Monday-Friday 9 am to 6 pm EST, 806-352-2519.)

This page may be copied and distributed in whole.   Kay Hoover, M. Ed., IBCLC 2011

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